Beyond informing us of the $9,106,906 AO made this weekend (coming in at #5), Box Office Mojo tells us nothing about the animated feature's budget. Howsoever, the Business Standard of India gives us this:
... Toy Story 3 was produced at a cost of $200 million and released in over 4,000 screens in the US. It had collected $110 million in its opening weekend.
Considering that Alpha and Omega has managed to recover around 25 per cent of its production cost through theatrical collections, the film is expected to generate cash profits for its makers. ...
Doing the math, and assuming that Business Standard is correct*, Alpha and Omega cost approximately $36 to $40 million, roughly half of the production cost of Despicable Me, the other foreign-made CGI feature of recent vintage.
I'll stay with my earlier prediction that it will collect $20-$35 million in domestic theatrical grosses and be set up for healthy DVD sales. A commenter noted that there wasn't much merchandise out with the picture, but the holiday season is still to come.
The feature won't be a big hit, but should end up a money-maker.
Add On: * I managed to overlook the "45 million" budget quote in another paragraph. The Standard managed to misstate (I think) the percentage that had been recovered. Assuming that BS is talking about theatrical grosses as a percentage of production costs, AO's weekend gross would have been $11.3 million and not $9.1 million.
(H/t to VFX Soldier for bringing the Business Standard article to our attention.)